Neonatal lupus erythematosus: Report of a case with cutaneous, hematological and hepatobiliary findings.
نویسندگان
چکیده
Neonatal lupus erythematosus is an autoimmune disorder mainly affecting the heart and skin. It is the most common cause of congenital heart block. In addition, hematological, hepatobiliary and neurological involvement may occur. Herein, we report a 23-day-old infant presented with annular, erythematous, and scaly and atrophic lesions on the face and trunk. Based on the clinical, laboratory and histopathological findings, she was diagnosed as neonatal lupus erythematosus. Neonatal lupus eryhtematosus should be considered in infants presenting with annular skin lesions, and we present this case to highlight the value of high index of clinical suspicion in diagnosis.
منابع مشابه
Cutaneous Lupus Erythematosus in Neonates and Infants: Maternally Derived Autoimmunity and the Neonatal Lupus Syndrome
Neonates are not sufficiently immunologically competent to develop IgG autoantibody–mediated disease independently. However, IgG autoantibodies from the mother transmitted in utero can initiate disease in susceptible individuals. In a small percentage of fetuses and neonates exposed to maternal autoantibodies of the Ro/SSA family, an autoimmune disease called “neonatal lupus erythematosus (NLE)...
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ورودعنوان ژورنال:
- The Turkish journal of pediatrics
دوره 58 1 شماره
صفحات -
تاریخ انتشار 2016